Epithelioid hemangioendothelioma in the right auricle of an adult, male Rhesus macaque (Macaca mulatta)

Autor: E D, Lombardini, R, Virmani, T W, Blanchard, J F, Lafond, S, Ménard, M, Doré
Rok vydání: 2010
Předmět:
Zdroj: Journal of medical primatology. 39(5)
ISSN: 1600-0684
Popis: A 9-year-old, male castrate, Rhesus macaque was euthanized following a prolonged history of chronic renal failure.Necropsy revealed a proliferative lesion within the right cardiac auricle composed of neoplastic epithelioid cells which infiltrated the myocardium and frequently exhibited intracytoplasmic luminae. Cells multifocally exhibited strong cytoplasmic immunoreactivity for Factor VIII-related protein (von Willebrand's factor).The histological characteristics of this tumor are consistent with a diagnosis of epithelioid hemangioendothelioma, an intermediate-grade vasoformative neoplasm which has to our knowledge not previously been reported in the heart of a non-human species.
Databáze: OpenAIRE