[The results of a controlled field trial of a dried erythrocytic immunoglobulin diagnostic agent for detecting the hepatitis A virus antigen]

Autor: M A, Gorbunov, N M, Nikitiuk, Iu F, Solov'ev, L G, Karpovich, T V, Kalashnikova, A R, Reĭzis, V A, Anan'ev, N V, Doroshenko, M A, Donets, M O, Favorov
Rok vydání: 1991
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (11)
ISSN: 0372-9311
Popis: The results of the controlled field trial of lyophilized erythrocytic immunoglobulin diagnosticum for the detection of hepatitis A virus antigen in the urine and feces of patients are presented. This diagnosticum was used for the study of urine and fecal samples from 225 patients (of these, 176 had hepatitis A) and 54 healthy persons in the passive hemagglutination (PHA) test. Their blood sera were studied in the PHA test (to detect HBsAg) and the radioimmunoassay (to detect anti-HAV IgM). The immunoglobulin diagnosticum under study was found to be nonspecific and faintly sensitive and, therefore, unsuitable for use in medical practice.
Databáze: OpenAIRE