| Autor: |
V K, Muratov, A T, Mevkh, N D, Igumnova, V V, Churiukanov, S D, Varfolomeev |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
Farmakologiia i toksikologiia. 50(1) |
| ISSN: |
0014-8318 |
| Popis: |
A combined effect on the irreversible inhibitor aspirin and fast reversible inhibitors ibuprofen, naproxen and sodium salicylate on prostaglandin-H-synthetase was studied on microsomal fractions from ram vesicular glands. The fast reversible inhibitors were shown to bind to prostaglandin-H-synthetase at the same site as aspirin and thereby to protect the enzyme against irreversible inactivation by aspirin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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