| Autor: |
Abby, Wills, Guang, Fan, Edward, Kim, Craig Y, Okada, Kevin P, White, R Samuel, Hopkins |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Dermatology online journal. 25(9) |
| ISSN: |
1087-2108 |
| Popis: |
A 55-year-old man with relapsing-remitting multiple sclerosis on fingolimod presented to the dermatology clinic with skin lesions on the left temple and cheek. Histopathology showed a diffuse infiltrate of enlarged, atypical lymphocytes throughout the dermis with an overlying grenz zone and a subpopulation of scattered smaller lymphocytes and plasma cells. Epstein-Barr virus-encoded RNA in situ hybridization stain was positive. Based on the morphologic and immunophenotypic findings, a diagnosis of EBV-positive diffuse large B-cell lymphoma was made. This case aims to raise awareness for the dermatologist that patients on fingolimod may be at increased risk of lymphoproliferative disorders. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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