| Autor: |
Yan, Liang, Pin, Tu, Xuan, Wang, Xiao-Ming, Yi, Xiao-Die, Zhou, Qun-Li, Shi |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Zhonghua nan ke xue = National journal of andrology. 25(7) |
| ISSN: |
1009-3591 |
| Popis: |
To investigate the clinical and histopathologic features of testicular seminoma with syncytoplasmic trophoblastic components.Using light microscopic staining, we analyzed the clinical and histopathologic characteristics, diagnosis, differential diagnosis and prognosis of 3 cases of testicular seminoma with syncytoplasmic trophoblastic components, and reviewed the relevant literature.All the 3 cases were typical seminoma with syncytiotrophoblastic giant cells. Immunohistochemistry showed strong expressions of CD117 OCT-4, SALL4 and PLAP in diffuse tumor cells, and that of hCG in syncytiotrophoblastic cells. Continuous monitoring and consultation exhibited normal levels of serum β-hCG in all the cases after postoperative chemotherapy.Testicular seminoma with syncytiotrophoblastic giant cells and increased serum β-hCG is a rare subtype, which occurs mostly in young people, sensitive to chemotherapy postoperatively and with a relatively good prognosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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