| Autor: |
Guangyu, Ma, Mingzhe, Shao, Baixuan, Xu, Jiahe, Tian, Yingmao, Chen |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Quantitative imaging in medicine and surgery. 9(6) |
| ISSN: |
2223-4292 |
| Popis: |
BACKGROUND: This study was performed to examine the effect of non-synchronization of the radiotracer injection and image acquisition on estimates of the glomerular filtration rate (GFR) by the Gates’ method. METHODS: A total of 218 volunteers were selected as the research subjects. Two-sample method (GFR(dt)) and (99m)Tc-DTPA dynamic renal imaging (GFR(Gates)) were used for determination of the GFR. We took GFR(dt) as the reference method, and then took the peak time of blood perfusion phase as the new time origin to ensure that all patients were unified on the time-radioactivity count rate curve. We moved the radioactivity curve on 9 time points to simulate premature (+20/+15/+10/+5 seconds), synchronous (0 seconds), and delayed (−20/−15/−10/−5 seconds) image acquisition in relation to the completion of tracer injection; we then acquired 9 GFR(Gates). The correlation and consistency of GFR(Gates) and GFR(dt) were analyzed. Variance analysis compared the differences between different GFR(Gates). RESULTS: All 9 GFR(Gates) had good correlation with GFR(dt). GFR(dt) and GFR(Gates) derived from −5, −10 and −15 s had the best correlation (r=0.827, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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