| Autor: |
N D, Nikiforov, M N, Trofimova, Iu A, Il'inskiĭ, S G, Mamontov, E V, Ivannikov |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR. (4) |
| ISSN: |
0869-2106 |
| Popis: |
Clinical and morphological characteristics were studied for a course of acute viral hepatitis A and delta with long-term cholestatic syndrome in asymptomatic carriers of HBsAg. 149 patients with moderate disease were examined, 53 of them had long-standing cholestasis syndrome. 96 viral hepatitis patients free of cholestasis served control. It is believed that the emergence of long-term intrahepatic cholestasis may be due to the following mechanisms of sinusoid lumina as a result of a drastic enlargement of multinuclear hepatocytes, hyperplasia and hypertrophy of Kupffer's cells. impaired binding of bilirubin in zone III of hepatic acinus. In cholestatic form of hepatitis A there occurs more pronounced reduction of sinusoid volume compared to other variants of viral hepatitis run. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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