| Autor: |
Le, Luo, Chunyou, Lai, Tianhang, Feng, Yutong, Yao, Hua, Xue, Guangming, Xiang, Lanyun, Luo, Xiaolun, Huang |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Am J Transl Res |
| ISSN: |
1943-8141 |
| Popis: |
Objective: To investigate effects of umbilical cord blood-derived mesenchymal stem cells (UC-MSCs) transplantation on the risks of liver cancers in end-stage liver disease (ESLD) patients. Methods: Data of 45 ESLD patients received UC-MSCs transplantation (UC-MSCs group) and 50 ESLD patients received non-UC-MSCs transplantation (non-UC-MSCs group) were retrospectively analyzed, and they were followed up for 5 years. Results: The incidence of liver cancer was much lower in UC-MSCs group than that in the non-UC-MSCs group (12% vs 2.2%, P=0.008). The survival rate of patients was significantly higher in the UC-MSCs group than that in the non-UC-MSCs group during the five years follow-up (P=0.043). The inflammation and fibrosis scores were lower in the UC-MSCs group than those in the non-UC-MSCs group (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
