| Autor: |
I, Nyman, L, Wallentin, M, Areskog, N H, Areskog, E, Swahn |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
International journal of cardiology. 39(2) |
| ISSN: |
0167-5273 |
| Popis: |
After stabilization of symptoms by medication a predischarge exercise test was performed in 855 men admitted with suspected unstable angina (54%) or non-Q-wave myocardial infarction (46%). Multiple logistic regression analysis demonstrated that the number of leads with ST-depression at exercise, low maximal work load, increasing age and ST-elevation in electrocardiogram at rest had independent prognostic value concerning the risk of myocardial infarction or death during the following year. Therefore a combination of extension of ST-depression and peak work load was used to define 'high and low risk response' at the exercise test. After 1 year the mortality in patients with 'high risk' compared to 'low risk' exercise response was 3.6% and 0% (P0.001) and the risk of either myocardial infarction or death was 15.4% and 3.9% (P0.0001), respectively. ST-depression, occurrence of angina and low peak load at exercise were independent predictors of future severe angina. After 1 year 29.5% of patients with any of these indicators at exercise had incapacitating symptoms that necessitated referral for coronary angiography compared to 4.8% in the group without these findings (P0.0001). The predictive value of the exercise test remained high in subgroups based on inclusion diagnosis, age or findings in electrocardiogram at rest and independently of treatment with beta-blockade, other antianginal medication or aspirin at the time of the exercise test. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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