| Autor: |
Kerstin K, Soelberg, Peter, Grupe, Henrik, Boel-Jørgensen, Peter H, Jørgensen, Søren, Fast, Viveque E, Nielsen, Laszlo, Hegedüs, Steen J, Bonnema |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Danish medical journal. 61(2) |
| ISSN: |
2245-1919 |
| Popis: |
(99m)Tc-pertechnetate scintigraphy is much used in the evaluation of patients with nodular goitre. We investigated the ability of experienced observers to estimate the thyroid 24-h (131)I uptake (RAIU) and the thyroid volume by visual evaluation of the scintigram.Two endocrinologists and two nuclear medicine specialists visually evaluated thyroid scintigrams from 171 patients with nodular goitre. The variables were assessed in a blinded fashion according to predefined categories and then compared with the true values. The assessments were repeated after four weeks. Kappa (κ ω) statistics were used.There was a low probability (range 6-22%) for the observers to assess the thyroid RAIU correctly. The probability of assessing the thyroid volume correctly was in the 14-22% range. Endocrinologists tended to underestimate the thyroid RAIU, mostly in patients with a RAIU30%. All observers significantly underestimated the thyroid volume if this was80 ml. There was a low interobserver agreement for the thyroid RAIU assessment (κ ω-values: 0.03-0.43) as well as for the thyroid volume assessment (κ ω-values: 0.19-0.48). The corresponding κ ω-values for the intraobserver agreement were 0.34-0.68 and 0.37-0.62, respectively. Nuclear medicine specialists achieved a significantly higher agreement than endocrinologists in their evaluation of both thyroid parameters.Thyroid (99m)Tc scintigraphy has poor interobserver agreement and is inaccurate for assessment of quantitative thyroid parameters, even when performed by experienced specialists.This study was supported by grants from the Danish Agency for Science, Technology and Innovation.not relevant. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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