1-(4-Phenoxybenzyl) 5-Aminouracil Derivatives and Their Analogues – Novel Inhibitors of Human Adenovirus Replication

Autor:	Nikitenko, N. A., Gureeva, E. S., Ozerov, A. A., Tukhvatulin, A. I., Izhaeva, F. M., Prassolov, V. S., Deryabin, P. G., Novikov, M. S., Logunov, D. Y.
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	inorganic chemicals animal structures organic chemicals polycyclic compounds Human adenovirus 5-aminouracil derivatives heterocyclic compounds Molecular Biology inhibitors of adenovirus replication adenovirus replication Research Article
Zdroj:	Acta Naturae
ISSN:	2075-8251
Popis:	Adenovirus infections are characterized by widespread distribution. The lack of causal therapy, which is effective in treating this group of diseases, explains the need for new therapeutic drugs. Notably, anti-adenoviral activity of [4-(phenoxy)benzyl]-5-(phenylamino)-6-azauracil, 1-[4-(phenoxy)benzyl]-5-(morpholino) uracil, 1-[4-(4-chlorophenoxy)benzyl]-5-(morpholino) uracil, and 1-[4-(4-fluorophenoxy)-benzyl]-5-(morpholino) uracil was observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::98c8bfd53fcdfd0d52280dc6b8dc6225 http://europepmc.org/articles/PMC6087815 Zobrazit plný text záznamu