| Autor: |
Dan, Yin, Xiao-yi, Wang, Xue-bin, Yan, Wei-hua, Liao |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 30(6) |
| ISSN: |
1672-7347 |
| Popis: |
To explore the correlation between microvascular density (MVD) and dynamic contrast-enhanced MRI in the glioma.We examined 35 patients with histologically verified glioma. Gadolinium-enhanced dynamic TurboFLASH imaging was performed preoperatively in all patients followed by conventional MRI. The steepest slope (SSmax) of curve and corresponding Tm1 in "first-pass" phase were obtained by analyzing time-signal curve. All specimens were immunostained with anti-human Factor VIII relative antigen monoclonal antibody postoperatively by streptavidin-peroxidase method to obtain the MVD. The correlation between SSmax, Tm1, and MVD was analyzed.SSmax was positively correlated with MVD (r = 0.640, P0.01). Tml was negatively correlated with MVD (r = -0.671, P0.01).The MVD correlates obviously with SSmax and Tml in the glioma. Analyzing the time-signal curve of dynamic contrast-enhanced MRI is helpful to predict the angiogenesis in the glioma. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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