[Successful treatment of postoperative multiple hepatic recurrence with hepatic arterial infusion of cisplatin and degrable starch microspheres]
| Autor: | Masahiro, Murakami, Takeshi, Tono, Mitsunobu, Imazato, Hirotoshi, Takemoto, Tadashi, Asaoka, Kazuyuki, Okada, Toshiyuki, Kanoh, Takashi, Iwazawa, Tadashi, Ohnishi, Yoshiaki, Nakano, Hiroshi, Yano, Masakatsu, Kinuta, Jyun, Okamura, Takushi, Monden |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Carcinoma Hepatocellular Portal Vein Liver Neoplasms Antineoplastic Agents Starch Thrombosis Infusion Pumps Implantable Drug Administration Schedule Hepatic Artery Biomarkers Tumor Hepatectomy Humans Infusions Intra-Arterial Prothrombin Chemoembolization Therapeutic Cisplatin Neoplasm Recurrence Local Protein Precursors Biomarkers |
| Zdroj: | Gan to kagaku ryoho. Cancerchemotherapy. 30(11) |
| ISSN: | 0385-0684 |
| Popis: | A 38-year-old man had multiple recurrence of hepatocellular carcinoma (HCC) with portal vein thrombosis after hepatectomy and postoperative transcatheter arterial chemotherapy with 5-fluorouracil (5-FU). He was treated by trans hepatic arterial embolization (TAE) with 100 mg of cisplatin (CDDP) and degrable starch microspheres (DSM). After 3 courses were administered, the recurrent lesions almost disappeared on CT, and the postoperative rise in PIVKA-II level and AFP level normalized. There were no side effects except slight fever and general fatigue. We recognized a partial response, and the patient is still alive 14 months after hepatectomy. This case suggests that TAE with CDDP and DSM might be useful for prolonging the survival of advanced HCC patients. |
| Databáze: | OpenAIRE |
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