| Autor: |
Corrado, Tamburino, Davide, Capodanno, Massimiliano, Mulè, Marilena, Scarabelli, Valeria, Cammalleri, Marco, Barbanti, Antonio, Calafiore, Gianpaolo, Ussia |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
The Journal of invasive cardiology. 21(3) |
| ISSN: |
1557-2501 |
| Popis: |
Percutaneous aortic valve replacement (PAVR) is an emerging alternative for high-risk patients with severe aortic stenosis. The aim of this study was to report acute and short-term outcomes of PAVR with the 18 Fr CoreValve Revalving System.From January 2007 to July 2008, 69 high-risk symptomatic patients with severe aortic stenosis were screened to assess their eligibility criteria for PAVR. All candidates were evaluated by a cardiac surgeon and a cardiologist. Thirty patients (13 men, 17 women, ages 82 +/- 5 years, range 73-88 years) met all the eligibility criteria and were enrolled in the study.Twenty-nine patients (97%) underwent successful valve implantation by a retrograde approach, with improvement in valve area (0.61 +/- 0.18 cm(2) to 1.49 +/- 0.39 cm(2); p0.001) and transvalvular gradient (58.1 +/- 17.6 mmHg to 9.2 +/- 4.0; p0.001). Paravalvular leakages were 1+ (n = 12) and 2+ (n = 2). Procedural success was achieved in 93% of patients, with 1 case of pericardial tamponade occurred during the first 48 hours after implantation. At 30-day mortality was 7%. The mean NYHA Functional Class declined from 2.72 +/- 0.59 to 1.31 +/- 0.47 (p0.001). No other major adverse events occurred at a mean follow up of 4.9 +/- 4.0 months (range 1-13 months).Our initial experience of PAVR in a cohort of older and high-risk surgical patients has been positive, with excellent acute and encouraging short-term results in terms of safety and efficacy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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