Posterior intracorneal opacities in patients with HIV infection

Autor:	Jennifer E, Thorne, Kayur H, Shah, Diane M, Brown, Gary N, Holland, Douglas A, Jabs
Rok vydání:	2005
Předmět:	Adult CD4-Positive T-Lymphocytes Male Visual Acuity HIV Infections Hyperlipidemias Middle Aged CD4 Lymphocyte Count Cholesterol Corneal Opacity Antiretroviral Therapy Highly Active Humans Descemet Membrane Triglycerides Retrospective Studies
Zdroj:	Ocular immunology and inflammation. 13(1)
ISSN:	0927-3948
Popis:	To describe a keratopathy in patients with the human immunodeficiency virus (HIV) infection.Retrospective review of ophthalmic and medical records, including laboratory evaluations, of seven patients with HIV infection and posterior intracorneal opacities.Each patient had a bilateral peripheral keratopathy located at the level of the Descemet membrane that was unassociated with intraocular inflammation. All patients were receiving highly active antiretroviral therapy (HAART). All patients had elevations in their CD4+ T-lymphocyte counts due to HAART prior to presenting with the corneal opacities. Five of the seven patients had elevated serum cholesterol, triglycerides, or both. Best-corrected visual acuity was 20/25 or better in six of the seven patients at the time of diagnosis, and vision remained stable through the follow-up period in all patients (median follow-up: 25 months; range: 14-82 months). The corneal opacities remained unchanged in all seven over the follow-up period.These patients have a bilateral keratopathy that appears to be non-progressive and has no effect on visual acuity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::97f17686c077ffe76aacc5340b01b10e https://pubmed.ncbi.nlm.nih.gov/15804766 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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