| Autor: |
J, Cea García, P A, de la Riva Pérez, I, Rodríguez Jiménez, F, Márquez Maraver, A, Polo Velasco, J, Jiménez Gallardo, M V, Aguilar Martín, T, Cambil Molina, M N, Cabezas Palacios |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Revista espanola de medicina nuclear e imagen molecular. 37(6) |
| ISSN: |
2253-8089 |
| Popis: |
Sentinel lymph node biopsy (SLNB) was created to reduce the morbidity associated with pelvic lymphadenectomy in the early stages of cervical cancer (CC), preserving its prognostic information. The goal is to assess the diagnostic validity of SLNB in CC in initial stages (IA1 with lymphovascular infiltration (LVI) +, IA2, IB1 and IIA1), thus avoiding unnecessary lymphadenectomies in many of the cases.From January 2012 to April 2017, 23 patients with initial stages of CC were included in a cross-sectional study to evaluate the effectiveness of the SLNB in CC with a mixed technique of cervical injection ofThe detection rate of SLNB with the mixed technique was 95.65%, with a negative predictive value (NPV) of 95.45% and sensitivity (S) of 100% in the case of bilateral drainage. The mean of excised SN was 3 (range 1-5). The bilateral detection rate in laparoscopy was 85.35%. The concordance between SPECT/CT and laparoscopy for the number and bilaterality of the SN using the Pearson coefficient was r = 0.727 and r = 0.833, respectively; p = 0.01. We only found one SN with a deferred result of micrometástasis and one false negative was detected.SLNB in CC using a mixed technique has a high detection and bilateral drainage rate, but S is still low if we include cases of unilateral drainage. A greater number of cases and the development of intraoperative ultrastaging could increase the S of the technique and to reduce the number of false negatives. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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