Gluconeogenesis and glycogen metabolism during development of Pacific abalone

Autor: Mugen, Koyama, Fumiya, Furukawa, Yuka, Koga, Shohei, Funayama, Suehiro, Furukawa, Otto, Baba, Ching-Chun, Lin, Pung-Pung, Hwang, Shunsuke, Moriyama, Sei-Ichi, Okumura
Rok vydání: 2020
Předmět:
Zdroj: American journal of physiology. Regulatory, integrative and comparative physiology. 318(3)
ISSN: 1522-1490
Popis: In lecithotrophic larvae, egg yolk nutrients are essential for development. Although yolk proteins and lipids are the major nutrient sources for most animal embryos and larvae, the contribution of carbohydrates to development has been less understood. In this study, we assessed glucose and glycogen metabolism in developing Pacific abalone, a marine gastropod mollusc caught and cultured in east Asia. We found that glucose and glycogen content gradually elevated in developing abalone larvae, and coincident expression increases of gluconeogenic genes and glycogen synthase suggested abalone larvae had activated gluconeogenesis and glycogenesis during this stage. At settling, however, glycogen sharply decreased, with concomitant increases in glucose content and expression of
Databáze: OpenAIRE