Antimicrobial and wound healing properties of a bacterial cellulose based material containing

Autor:	I S, Savitskaya, D H, Shokatayeva, A S, Kistaubayeva, L V, Ignatova, I E, Digel
Rok vydání:	2019
Předmět:	Bacterial cellulose Wound healing Microbiology Microbial biotechnology Biocomposite Article Biotechnology Bacillus subtilis
Zdroj:	Heliyon
ISSN:	2405-8440
Popis:	A biocomposite composed of bacterial cellulose (BC) gel-film and Bacillus subtilis (BS) cells was obtained and characterized with a view to future biomedical applications. The inclusion of functional ingredient (1010/g viable BS cells) in the composite was carried out by their joint aggregation with the BC gel-film. Immobilized BS cells displayed high antagonistic activity towards causative agents of wound infections such as Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa. Application of the BC/BS-biocomposite for the treatment of excision wounds, performed on laboratory animals, stimulated reparative processes and shortened the healing time. Possible mechanisms of the wound-healing effect of BC/BS gel films are discussed. In this work we claim that the developed BC/BS-material can be positioned as a universal wound coating and sanitary-hygienic product. Microbiology; Biotechnology; Microbial biotechnology; Bacterial cellulose; Wound healing; Bacillus subtilis; Biocomposite
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::97a0e0e1a46d6cd25e57fabf2df453a1 https://pubmed.ncbi.nlm.nih.gov/31667414 Zobrazit plný text záznamu