| Autor: |
Fei-zhao, Jiang, Heng-liang, Zhu, Xiao-feng, Zheng, Jin-fu, Tu, Hong, Lin, Ru-ying, Hu, Xiong, Chen, He-yi, You, Zhen-xu, Zhou, Wei-Jian, Zhang, Hua-Jie, Cai |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery. 15(1) |
| ISSN: |
1671-0274 |
| Popis: |
To investigate the efficacy and feasibility of duodenojejunal bypass(DJB)on non-severe obese patients with type 2 diabetes mellitus(T2DM).The body mass index (BMI), fasting plasma glucose(FPG), 2h-postprandial plasma glucose(2hPG), fasting insulin(F-ins), fasting c-peptide(F-CP), glycated hemoglobin and hypoglycemic agents dose changes were tested in 7 patients with non-severe obese T2DM undergoing DJB, preoperatively and within 24 weeks after surgery during the follow-up. Data were collected and the clinical outcomes of T2DM were analyzed.In 7 cases of non-obese T2DM who underwent DJB, one patient was weaned off hypoglycemic agents with normal FPG, 2hPG and HbA1c postoperatively. Five required significantly lower dosage. No significant improvement in 1 case. Complete remission rate of hyperglycemia was 1/7, effective rate was 6/7, and effective rate of HbA1c was 5/7. No significant changes in BMI were observed between the preoperative and postoperative phases.Plasma glucose level can be markedly reduced by duodenojejunal bypass in non-obese T2DM, independent of weight loss, and the mechanism remains unclear. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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