[Inhibitor participation in the regulation of serum RNAse activity in the formation of immunity against influenza]

Autor: M S, Parfenova, M B, Maksimovich, S I, Bukovetskiĭ, V A, Tishechkina, S P, Lisovaia
Rok vydání: 1976
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (6)
ISSN: 0372-9311
Popis: It was shown that parenteral administration of lead ions caused in the blood serum of albino mice a significant decrease in the amount of the bound RNA-ase 1 inhibitor and a simultaneous increase in the activity of this enzyme. Consequently, this inhibitor served as a regulator of the serum RNA-ase 1 activity. A considerable increase in the amount of the bound and free RNA-ase 1 inhibitor was noted in the serum in the process of triple immunization of persons with live influenza vaccine; this was accompanied by a significant reduction of the free RNA-ase 1 activity. This indicated that along with other mechanisms the inhibitor apparently participated in the processes of formation of immunity against influenza.
Databáze: OpenAIRE