| Autor: |
Frederik Banch, Clausen, Grethe Risum, Krog, Klaus, Rieneck, Leif Kofoed, Nielsen, Rasmus, Lundquist, Kirsten, Finning, Ebbe, Dickmeiss, Morten, Hedegaard, Morten Hanefeld, Dziegiel |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Ugeskrift for laeger. 168(26-32) |
| ISSN: |
1603-6824 |
| Popis: |
We present a reliable test for prenatal prediction of fetal RhD type using maternal plasma from RhD-women. This test is needed for a future antenatal RH prophylaxis. A new real time PCR based assay targeting RHD exon 7 and a published assay for RHD exon 10 were used to determine the fetal RHD status in DNA extracted from plasma from 56 pregnant women in 15th-36th week of gestation. Prediction of fetal RhD type was compared with the phenotype determined after birth, and showed 100% concordance. This setup will be of value in antenatal RH prophylaxis and in the management of immunised women. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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