Differential effects of fasting and nicotinic acid on various enzymatic activities of the 9,000 g fraction of the perfused rat liver

Autor:	I, Bartosek, A, Guaitani, A, Guindani
Rok vydání:	1975
Předmět:	Male Nitroanisole O-Demethylase Aniline Compounds Time Factors Pyridines Nicotinic Acids Aniline Hydroxylase Fasting Stimulation Chemical Mixed Function Oxygenases Rats Perfusion Depression Chemical Microsomes Liver Animals Isonicotinic Acids Aminopyrine Oxidoreductases Aminopyrine N-Demethylase
Zdroj:	Pharmacology. 13(3)
ISSN:	0031-7012
Popis:	Perfused livers obtained from rats fasted for 24 or 48h show a marked impairment of the N-demethylation (substrate aminopyrine) without major changes of the O-demethylation (p-nitro anisol) and hydroxylation (aniline). The infusion with nicotinic acid restored N-demethylation but it inhibited O-demethylation and hydroxylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::96e11a5a5ae6aa3556c0d2a70e0c8193 https://pubmed.ncbi.nlm.nih.gov/1153505 Zobrazit plný text záznamu