[Effectiveness of Osimertinib for Postoperative Recurrence of Lung Cancer with L861Q Activating EGFR Mutation:Report of a Case]

Autor: Motoaki, Yasukawa, Takeshi, Kawaguchi, Masahide, Ota, Takashi, Tojo, Shigeki, Taniguchi
Rok vydání: 2021
Předmět:
Zdroj: Kyobu geka. The Japanese journal of thoracic surgery. 74(2)
ISSN: 0021-5252
Popis: A 69-year-old woman was referred to our hospital because of an abnormal shadow on a chest roentgenogram at a medical check-up. Chest computed tomography showed a 2.5 cm-diameter tumor in the right pulmonary lower lobe. Fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) could not detect the other lesions. The patient underwent thoracoscopic right lower lobe lobectomy for lung adenocarcinoma. Pathological diagnosis was invasive adenocarcinoma (pT1cN0M0). EGFR status was positive for the L861Q mutation in exon 21. At 31 months after surgery, the recurrence appeared as vertebral and multiple pulmonary lesions, and the treatment with osimertinib showed satisfactory response seven months after starting the treatment.
Databáze: OpenAIRE