| Autor: |
F, Limaïem, A, Lahmar, C, Ben Fadhel, S, Bouraoui, S, M'zabi-Regaya |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Pathologica. 100(1) |
| ISSN: |
0031-2983 |
| Popis: |
Gynandroblastoma is a rare variant of ovarian sex cord stromal tumours that demonstrates morphological evidence of both male and female differentiation. We report a new case of gynandroblastoma in a 22-year-old nulliparous female with a history of menstrual disturbance. Physical examination disclosed a painless pelvic mass measuring 20 cm across with normal secondary sex characteristics, and no signs of virilisation. Histological examination of the surgically resected primary tumour revealed a predominant adult granulosa cell component admixed with a minor Sertoli cell component that did not exceed 20% of the tumour. Immunohistochemical analysis showed positive immunostaining of Sertoli cell areas with inhibin. The final diagnosis was gynandroblastoma. The post-operative course was uneventful and there was no evidence of recurrence during the 9-month follow-up period. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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