| Autor: |
Tze-Fan, Chao, Chih-Hung, Lai, Ta-Chuan, Tuan, Tsu-Juey, Wu, Jin-Long, Huang, Chuen-Wang, Chiou, Hsiang-Chiang, Hsiao, Yenn-Jiang, Lin, Jo-Nan, Liao, Chi-Woon, Kong, Shih-Ann, Chen |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Acta Cardiologica Sinica. 30(1) |
| ISSN: |
1011-6842 |
| Popis: |
The use of an implantable cardioverter-defibrillator (ICD) has a proven capacity to prevent sudden cardiac death (SCD), and can also improve survival duration in well-selected patients. The goal of the present study was to investigate the long-term prognosis and predictors of mortalities among ICD recipients in Taiwan.From 1998 to 2009, 238 consecutive patients who experienced SCDs or life-threatening ventricular tachyarrhythmias without correctable causes and received ICD implantations in 3 medical centers (Taipei, Taichung and Kaohsiung Veterans General Hospital) were enrolled in this study. The clinical endpoint was defined as the occurrence of all-cause mortality during the follow-up.The mean age of the patients was 63.0 ± 15.3 years, and 76.5% of them were male. Ischemic cardiomyopathy was the leading cause for the ICD implantations (39.1%). During the mean follow-up duration of 36.8 ± 29.8 months, there were 48 patients (20.2%) who died. Patients with structural heart diseases had a higher mortality rate than those without such diseases. Additionally, old age, low left ventricular ejection fraction (LVEF) and a history of diabetes mellitus (DM) were significant predictors of mortality. The optimal cutoff values for age (70 years) and LVEF (40%) in predicting mortality were further identified using the receiver operating characteristic curves.Based on the ICD registry from 3 medical centers in Taiwan, the annual mortality rate was around 6.6% and was higher in those patients with structural heart diseases. We observed that old age, low LVEF and a history of DM were significant predictors of mortality.Implantable cardioverter-defibrillator; Mortality; Predictor; Taiwan. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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