| Autor: |
Mahsa, Mashayekhi, Milad, Asadi, Shahriar, Hashemzadeh, Amir, Vahedi, Dariush, Shanehbandi, Ahmad Faris, Al-Omar, Morteza, Akbari, Mortaza, Raeisi |
| Rok vydání: |
2022 |
| Zdroj: |
Hormone molecular biology and clinical investigationReferences. |
| ISSN: |
1868-1891 |
| Popis: |
Epigenetic alterations like methylation of tumor suppressor genes or oncogenes, in respiratory epithelium have been associated with lung cancer. Hypermethylation of genes promoter is an epigenetic event, and is responsible to tumor suppressor genes inactivation as well as oncogenes activation. This study aimed to assess the role of methylation status in promoter ofIn this study, we collected 100 tissue samples (50 lung cancer tissues and 50 adjacent non-cancerous lung tissues) from Iranian lung cancer patients. The genomic DNA was extracted, and methylation status of bothMethylation ofMethylation levels of both |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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