[Visualization of iron nanoparticles accumulation and distribution features in sensitive and resistant to antitumor drugs human breast cancer cells after different time intervals of cultivation with liposomal ferromagnetic]
| Autor: | L A, Nalieskina, N Iu, Luk'ianova, L M, Kuns'ka, D V, Demash, V F, Chekhun |
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| Rok vydání: | 2012 |
| Předmět: |
Cytoplasm
Time Factors Cell Survival Histocytochemistry Iron Cell Membrane Antineoplastic Agents Breast Neoplasms Endocytosis Kinetics Doxorubicin Drug Resistance Neoplasm Cell Line Tumor Liposomes Fiber Optic Technology Humans Female Molecular Targeted Therapy Cisplatin Magnetite Nanoparticles Cell Proliferation |
| Zdroj: | TSitologiia i genetika. 45(6) |
| ISSN: | 0564-3783 |
| Popis: | It was shown in vitro that visualization of iron nanoparticles by histochemical Lilly method, modified by authors for cytomorphological studies, could be a certain control of ferromagnetic income to human breast cancer MCF-7 cells with different sensitivity to antitumor drugs (doxorubicin and cisplatin). The form of the visualized iron nanoparticles, their localization and distribution towards intracellular structures was studied. It was shown that localization, dynamics of accumulation and release of ferromagnetic from cells were connected to their sensitivity to antitumor drugs and time of incubation with iron nanoparticles. |
| Databáze: | OpenAIRE |
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