Left ventricular function by strain in uncomplicated malaria: a prospective study from the Brazilian Amazon

Autor: Philip, Brainin, Laura Cordeiro, Gomes, Anna E, Holm, Luan O, Matos, Alma, Wegener, Karine O, Lima, Molly D, Kaagaard, Isabelle V M, Vieira, Rodrigo Medeiros, de Souza, Flemming Javier, Olsen, Claudio Romero Farias, Marinho, Tor, Biering-Sørensen, Odilson M, Silvestre
Rok vydání: 2022
Zdroj: The international journal of cardiovascular imaging.
ISSN: 1875-8312
Popis: We hypothesized that adults with uncomplicated malaria have lower left ventricular contractile function compared to the general population and that this improves after antimalarial treatment. We examined uncomplicated malaria and the general population from the Western part of the Brazilian Amazon Basin. All persons underwent an echocardiographic examination and peripheral blood smears. Left ventricular function was assessed by speckle tracking analysis of global longitudinal strain (GLS). Logistic regression models were used to assess the association between malaria status (yes/no) and GLS and improvement in GLS by follow-up was assessed using a paired T-test. We enrolled 99 adults with uncomplicated malaria (mean age 40 years, 46% female) of whom 75 had Plasmodium vivax, 22 Plasmodium falciparum and two had both species [median 1595 (528 to 6585) parasites/mm
Databáze: OpenAIRE