Persistent truncus arteriosus in monozygotic twins: case report and literature review

Autor:	C, Mas, M B, Delatycki, R G, Weintraub
Rok vydání:	1999
Předmět:	Male Diseases in Twins Infant Newborn Humans Female Twins Monozygotic Truncus Arteriosus Persistent In Situ Hybridization Fluorescence Pedigree
Zdroj:	American journal of medical genetics. 82(2)
ISSN:	0148-7299
Popis:	We report on a pair of monozygotic twins with persistent truncus arteriosus. They had no evident clinical signs of DiGeorge syndrome. Pathologic examination of the placenta and DNA analysis in chromosomes 7, 8, and 15 was consistent with monozygosity. Fluorescence in situ hybridization test was negative for chromosome 22q11 microdeletion. Family history revealed a female cousin with tetralogy of Fallot. The isolated presence of this conotruncal abnormality in monozygotic twins is extremely rare. The genetic considerations are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::951d1f5278bd87bd5035141ef2d52e5a https://pubmed.ncbi.nlm.nih.gov/9934979 Zobrazit plný text záznamu Plný text