| Autor: |
G W, Barone, W A, Hudec, D M, Sailors, B L, Ketel |
| Rok vydání: |
1996 |
| Předmět: |
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| Zdroj: |
Clinical transplantation. 10(4) |
| ISSN: |
0902-0063 |
| Popis: |
For combined kidney and pancreas transplant recipients infectious complications remain a major source of morbidity. With as many antibiotic protocols as transplant centers, the exact type and duration for prophylactic wound antibiotics remains undefined. A retrospective review of our series of 40 combined kidney and pancreas transplants was performed using a single 1 g dose of cefazolin preoperatively along with cefazolin bladder and intra-abdominal irrigation. Two patients developed superficial wound infections for a rate of 5% (2/37). The deep wound infection rate was 11% (4/37), and all followed either a bladder anastomotic leak or the initial development of transplant pancreatitis. Our overall rate of 16% is very comparable with other series of combined kidney and pancreas transplant recipients. To help eliminate the potential development of superinfections and resistant organisms, a single dose of antibiotics appears to be as effective for wound prophylaxis in these patients when compared to multiple-antibiotic and multiple-day regiments. A randomized prospective study of prophylactic antibiotics in combined kidney and pancreas transplants is needed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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