| Autor: |
Yan, Lu, Zi-Dun, Wang, Jing, Shen, Yao-Chu, Xu |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. |
| ISSN: |
0253-9624 |
| Popis: |
To evaluate the relationship between IL8-251 gene polymorphisms and gastric cancer.Literatures were reviewed and selected based on the criteria for inclusion. The Meta-analysis software, REVMAN 4.2, was applied to check the heterogeneity across the studies and calculating the pooled OR.Total of 2114 cases and 2505 controls from 8 studies for IL8-251 were included. The chi(2) value was 21.48 (P = 0.003), and the pooled OR of (AA + AT) vs. TT was 1.12 (95% CI 0.90 - 1.40). Large heterogeneity was found among the studies. After the sensitivity analysis, the pooled OR of (AA + AT) vs. TT 1.21 (95% CI 1.06 - 1.39).IL8-251-A allele might be associated with higher risk of developing gastric cancer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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