| Autor: |
N L, Edwards, D P, Recker, I H, Fox |
| Rok vydání: |
1980 |
| Předmět: |
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| Zdroj: |
Advances in experimental medicine and biology. |
| ISSN: |
0065-2598 |
| Popis: |
1. A daily urinary excretion of 0.8 percent of the administered radioactivity results from the turnover of the labeled adenine nucleotide pool. 2. A 4-fold increase of urinary radioactivity excretion occurs in patients with the Lesch-Nyhan syndrome and support the role of impaired hypoxanthine salvage in the purine overexcretion associated with HGPRT deficiency. 3. Our data do not support the possibility that the increased radioactivity excretion in the HGPRT deficient subjects results from an elevated rate of adenine nucleotide degradation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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