| Popis: |
The effect of sectioning the nephric lymphatic vessels on the functional morphology of its tissue elements has been studied in 125 dogs, providing that the other kidney, is preserved, as well as after contralateral nephrectomy and at autotransplantation. It has been stated that on the first postoperative days, in consequence of lymphostasis, protein resorption from the interstitial connective tissue is impeded. This results in stromal edema and in disturbed liquor transport performed by nephrocytes of the convoluted tubules. Protein retention in the interstilial connective tissue, despite the fact that lymph drainage is restored, produces formation of a slightly expressed diffuse nephric sclerosis with increasing number of collagenous fibrils, thickened basal membranes and accumulation of glycoproteids in them. Sectioning the nephric lymph vessels delays the development of compensatory hypertrophy signs in the nephric cellular elements. Nevertheless, as microcirculatory disturbances subside, hypertrophy and hyperplasy of cells and intracellular structures develop. Comparing dynamics of morphological changes in the autotransplanted kidney with that of a single kidney when its lymphatic vessels are cut, it is possible to conclude that it is the disorder in lymph drainage that causes a slight diffuse sclerosis in the transplanted kidney. |
