[SAYP interacts with DHR3 nuclear receptor and participates in ecdysone-dependent transcription regulation]

Autor:	N E, Vorob'eva, Iu V, Nikolenko, A N, Krasnov, Iu L, Kuz'mina, V V, Panov, E N, Nabirochkina, S G, Georgieva, Iu V, Shidlovskiĭ
Rok vydání:	2012
Předmět:	Transcriptional Activation Ecdysone Drosophila melanogaster Gene Knockdown Techniques Metamorphosis Biological Animals Drosophila Proteins Gene Expression Regulation Developmental Receptors Cytoplasmic and Nuclear Gene Regulatory Networks Chromatin Chromosomes Transcription Factors
Zdroj:	Genetika. 48(1)
ISSN:	0016-6758
Popis:	The role of metazoan coactivator SAYP in nuclear receptor-driven gene activation in the ecdysone cascade of Drosophila is considered. SAYP interacts with DHR3 nuclear receptor and activates the corresponding genes by recruiting the BTFly (Brahma and TFIID) coactivator supercomplex. The knockdown of SAYP leads to a decrease in the level of DHR3-activated transcription. DHR3 and SAYP interact during development and have multiple common targets across the genome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::94265f335b82772502eec8c467bedb70 https://pubmed.ncbi.nlm.nih.gov/22567850 Zobrazit plný text záznamu