[The genotypic profiles of Candida albicans isolates from patients with oral lichen planus]

Autor: Xin, Zeng, Qian-ming, Chen, Min-hai, Nie, Bing-qi, Li
Rok vydání: 2005
Předmět:
Zdroj: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 36(2)
ISSN: 1672-173X
Popis: The aim of this study was to investigate the genotypic profiles of Candida albicans isolates from erosive oral lichen planus (OLP) and non-erosive OLP.A total of 112 isolates obtained from healthy control (26), erosive OLP (62) and non-erosive OLP (24) were screened for genotypic profiles by using the randomly amplified polymorphic DNA (RAPD) assay.RAPD analyses with some random primer reavealed 4 different genotypes among all isolates, and there was significant difference in genotypic constitution between every two groups. Statistically, B and D were the major types in healthy group; A and C were the major types in erosive OLP; A and D were the major types in non-erosive OLP.Some Candida albicans isolates with special genotypic profiles may contribute to the development and progression of OLP.
Databáze: OpenAIRE