[Inhibiting contractility without necrosis: would it be helpful for hypertrophic cardiomyopathy? Experimental model of intramyocardial botulinum toxin and wortmannin]

Autor:	Francisco Javier, Roldán-Gómez, Natalia, Pavón-Martínez, Faustino, Gálvez-Pérez, Jesús, Vargas-Barrón
Rok vydání:	2012
Předmět:	Androstadienes Necrosis Botulinum Toxins Cardiomyopathy Hypertrophic Injections Intralesional Models Theoretical Wortmannin Myocardial Contraction
Zdroj:	Archivos de cardiologia de Mexico. 82(4)
ISSN:	1405-9940
Popis:	The purpose of this paper is to introduce a new idea: local inhibition of contractility without necrosis. It's potential usefulness in hypertrophic cardiomyopathy treatment is discussed and 2 pharmacological models, administrating botulinum toxin and wortmannin directly in the myocardium are disclosed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::93fd8ddcf9e0a4ca1890a855ba5de730 https://pubmed.ncbi.nlm.nih.gov/23164738 Zobrazit plný text záznamu