Immune responses to dialyzer contents by dialysis patients

Autor:	J E, Sherlock, R, Bachvaroff
Rok vydání:	1987
Předmět:	Immunodiffusion Renal Dialysis Humans Immunoglobulins Antigens Lymphocyte Activation Antibodies Immunosorbent Techniques
Zdroj:	Mineral and electrolyte metabolism. 13(6)
ISSN:	0378-0392
Popis:	Serum antibodies to the contents of cuprophan hollow-fiber dialyzers were demonstrated by immunodiffusion in 36 of 68 hemodialysis patients. The antibodies were not absorbed by ethylene oxide or washed cuprophan hollow fibers. No cross-reactivity with Escherichia coli lipopolysaccharide and pneumococcal polysaccharides was noted. The antibodies were IgM and probably IgG. Washed cuprophan hollow fibers did not absorb IgE detected by radioallergosorbent test (RAST). Lymphocyte transformation to the contents of both cuprophan hollow fiber and polyacrylonitrile plate dialyzers was demonstrated. Materials added in manufacture of dialyzers are immunogenic. The long-term biologic effects are unknown.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::93e9f4ee40a41eefded7fbe2a8bc85ac https://pubmed.ncbi.nlm.nih.gov/3121994 Zobrazit plný text záznamu