[Clinical study of fluid resuscitation guided by peripheral perfusion index in patients with septic shock]

Autor: Leqing, Lin, Wei, Cao, Dongcheng, Liang, Zhuxian, Zhang, Liang, Guo, Xiuli, Zhang, Baiyong, Wang
Rok vydání: 2022
Předmět:
Zdroj: Zhonghua wei zhong bing ji jiu yi xue. 34(6)
ISSN: 2095-4352
Popis: To explore the guiding effect of peripheral perfusion index (PI) on fluid resuscitation in patients with septic shock.Sixty-five patients with septic shock who were diagnosed according to relevant criteria of septic shock and admitted to the department of critical care medicine of the Affiliated Hospital of Hangzhou Normal University from September 2017 to December 2020 were included. Patients were divided into the conventional treatment group (30 cases) and PI guidance group (35 cases) by random number method. Both groups of patients were treated with the bundle according to clinical guidelines. Sputum, urine and blood were collected for pathogenic microorganism culture before the application of antibiotics, and vasoactive drugs were given. Both groups need to achieve all the following resuscitation goals within 6 hours: urine output0.5 mL×kgBefore fluid resuscitation, there were no statistically significant differences in all indicators between two groups. After 6 hours fluid resuscitation, the four treatment goals in PI guidance group were slightly lower than those of the conventional treatment group [HR (times/min): 96.5±12.1 vs. 97.7±7.9, MAP (mmHg): 83.2±6.2 vs. 82.1±7.5, ScvOThe peripheral PI can be used as an important indicator of fluid resuscitation in patients with septic shock. PI guiding fluid resuscitation in patients with septic shock can reduce Lac levels, shorten the duration of fluid negative balance and reduce the risk of fluid overload.
Databáze: OpenAIRE