Adenosine A

Autor: Silvia, Sgambellone, Silvia, Marri, Stefano, Catarinicchia, Alessandro, Pini, Dilip K, Tosh, Kenneth A, Jacobson, Emanuela, Masini, Daniela, Salvemini, Laura, Lucarini
Rok vydání: 2022
Předmět:
Zdroj: International journal of molecular sciences. 23(21)
ISSN: 1422-0067
Popis: Adenosine receptors (ARs) are involved in the suppression and development of inflammatory and fibrotic conditions. Specifically, AR activation promotes differentiation of lung fibroblasts into myofibroblasts, typical of a fibrotic event. Pulmonary fibrosis is a severe disease characterized by inflammation and fibrosis of unknown etiology and lacking an effective treatment. The present investigation explored the action of MRS5980, a new, highly potent and selective A
Databáze: OpenAIRE