A human HP1 pseudogene maps to chromosome 11p14

Autor:	A, Park, L, Holmer, H J, Worman
Rok vydání:	2000
Předmět:	Genomic Library DNA Complementary Base Sequence Chromobox Protein Homolog 5 Chromosomal Proteins Non-Histone Chromosomes Human Pair 11 Multigene Family Molecular Sequence Data Restriction Mapping Chromosome Mapping Humans DNA Pseudogenes
Zdroj:	Somatic cell and molecular genetics. 24(6)
ISSN:	0740-7750
Popis:	The chromo multigene superfamily encodes numerous proteins involved in chromatin structure or organization. The prototypical member of this superfamily is HP1 of Drosophila melanogaster. We now present the sequence of a human HP1Hs gamma pseudogene and assign it to chromosome 11p14 by radiation hybrid mapping. The coding regions of at least three other human genes for HP1 orthologues and another pseudogene are very similar in sequence. These results demonstrate that HP1-type sequences have been duplicated multiple times in the mammalian genome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9336a11e588060c80a543d9e60b78c0a https://pubmed.ncbi.nlm.nih.gov/10763413 Zobrazit plný text záznamu Full text from SpringerLink