| Autor: |
Jin-Lian, Liu, Xue-Jun, Liu, Ting-Ting, Ma, Jie-Run, Chen, Li-Lan, Li |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Zhongguo shi yan xue ye xue za zhi. 29(4) |
| ISSN: |
1009-2137 |
| Popis: |
To study the serological characteristics and molecular biological basis of 8 individuals with Para-Bombay phenotypes in Guangxi area.Serological tests were used to identify the blood groups of red cells. Molecular biological methods, including PCR-SSP for ABO genotyping and DNA sequencing for FUT1, were used to detect the genotypes of ABO and FUT1 which determined the expression of H antigen.Eight individuals in the study were all the Para-Bombay phenotypes, including 4 cases of BThere are varieties of molecular genetic mechanisms for Para-Bombay phenotypes. In this study, the FUT1 mutations that cause Para-Bombay phenotypes in Guangxi area are mainly h3, h广西地区8例类孟买血型个体的血清学鉴定及FUT1基因突变分析.对广西地区8例类孟买血型个体进行血清学及分子生物学背景分析。.采用血型血清学方法对研究标本进行血型鉴定，用分子生物学方法进行基因型分析，包括以PCR-SSP方法进行ABO基因分型和测序，对决定H抗原表达的FUT1基因进行分析。.8例类孟买血型中，4例为B类孟买血型存在多种分子遗传机制，在本研究中，广西地区类孟买血型个体中发现导致类孟买血型的FUT1基因突变主要包括h3、h |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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