Regulation of TNF-mediated cell death and inflammation by human adenoviruses

Autor:	L R, Gooding
Rok vydání:	1994
Předmět:	Adenovirus Infections Human Gene Expression Regulation Viral Inflammation Cell Death Tumor Necrosis Factor-alpha Adenoviruses Human DNA Viral Animals Humans Genome Viral Interleukin-1
Zdroj:	Infectious agents and disease. 3(2-3)
ISSN:	1056-2044
Popis:	Human adenoviruses are among a growing number of human, animal, and even plant viruses that encode gene products that interfere with the defense mechanisms of the host. The host mechanisms most often affected by these viral products are the innate and inflammatory responses such as interferon and the proinflammatory cytokines interleukin-1 (IL-1) and tumor necrosis factor (TNF). This review discusses examples of viral anti-immune mechanisms from many different viruses and then focuses on the molecular interactions between adenoviruses and TNF and the effect of these interactions on the ensuing pathogenesis of virus infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::924b40186bc25e748baf50fdeee6f05c https://pubmed.ncbi.nlm.nih.gov/7812649 Zobrazit plný text záznamu