| Popis: |
Brucellin INRA is a new allergen used for the screening of brucellosis. It shows, by a delayed-type skin hypersensitivity reaction, the sensitization induced in animals by a brucella infection. The biological potency of each batch must be compared to that of a standard allergen. The use of guinea-pigs necessary for this quality control and the statistical analysis of the results are described and discussed. The aim of this paper is to provide the end-user with a simple and accurate method, and to alert him to the difficulties and limits of such a test. |
