Adrenal corticosteroids cause gastrin cell hyperplasia

Autor: J P, Delaney, H M, Michel, M E, Bonsack, M M, Eisenberg, D H, Dunn
Rok vydání: 1979
Předmět:
Zdroj: Gastroenterology. 76(5 Pt 1)
ISSN: 0016-5085
Popis: Chronic exogenous high dose adrenal cortical steroid administration to dogs resulted in a 137% increase in G-cell mass with an associated enhancement of peak serum gastrin levels. Adrenalectomy caused a halving of G-cell numbers without significant changes in serum gastrin levels. Adrenal cortical steroids appear to have an important trophic role for the G-cell.
Databáze: OpenAIRE