[Dependence of the specific activity of an immunoglobulin against tick-borne encephalitis on the degree of its fragmentation]

Autor: V Iu, Gavrilenkova, T M, Kargina, T D, Shalamberidze, V F, Runova, M S, Vorob'eva
Rok vydání: 1987
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (1)
ISSN: 0372-9311
Popis: Immunoglobulin preparations against tick-borne encephalitis with the increasing content of Fab-fragments (from 16% to 45%) have been experimentally obtained. As revealed by testing these samples in vivo for specific activity (in the biological neutralization test), the preparations containing 16% of Fab-fragments show no perceptible decrease of specific activity; its sharp decrease (2-16 times) can be observed in preparations with a high degree of fragmentation (the content of Fab-fragments being equal to 30-45%).
Databáze: OpenAIRE