| Autor: |
A, Ishiki, R, Harada, N, Okamura, N, Tomita, C C, Rowe, V L, Villemagne, K, Yanai, Y, Kudo, H, Arai, S, Furumoto, M, Tashiro, K, Furukawa |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
European journal of neurology. 24(1) |
| ISSN: |
1468-1331 |
| Popis: |
Visualization of pathogenic protein aggregates is crucial to elucidate pathomechanisms and to make an accurate diagnosis in many neurodegenerative conditions. Aggregates of the microtubule-binding protein, tau, are one of the most important pathogenic molecules in neurodegenerative disorders. Progressive supranuclear palsy (PSP) is characterized by the deposition of tau proteins in some specific area such as the basal ganglia and brainstem. We tried to detect tau lesions in the brains of living patients with PSP with a novel positron emission tomography (PET) tracer, [Paraffin-embedded brain sections of the patients with PSP were used for autoradiography with [Autoradiography in the brain sections of patients with PSP demonstrated [We conclude that [ |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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