| Autor: |
D C, Rees, N H, Chapman, M T, Webster, J F, Guerreiro, J, Rochette, J B, Clegg |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
British journal of haematology. 105(2) |
| ISSN: |
0007-1048 |
| Popis: |
Venous thrombosis is a common problem, predominantly afflicting people of European origin. This European predisposition has been explained to some extent by the recent characterization of factor V Leiden, and the G20210A prothrombin variant. Although it is clear that factor V Leiden is largely confined to Europeans, the world distribution of the prothrombin variant is not known. We have analysed samples from 22 different non-European countries and shown that this prothrombin variant is very rare outside Europe: one case occurring in India. The reason for the confined distribution of these two mutations is unclear. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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