[ARCHITECT Chagas(®): a new diagnostic tool in Chagas disease]

Autor: M Asunción, Iborra-Bendicho, Miriam, Albert-Hernández, Carmen, Márquez-Contreras, Manuel, Segovia-Hernández
Rok vydání: 2011
Předmět:
Zdroj: Enfermedades infecciosas y microbiologia clinica. 30(8)
ISSN: 1578-1852
Popis: To evaluate a new chemiluminescent microparticle immunoassay (ARCHITECT Chagas(®), Abbott).In this study, 165 samples were tested by two different serological tests. The ARCHITECT Chagas(®) assay was performed using ARCHITECT i2000(SR) system (Abbott).The sensitivity and specificity of ARCHITECT assay was 100% and 96.6%, respectively. The concordance rate was 0.96 (95%CI: 0.92-1) for ELISA and 0.91 (95%CI: 0.85-0.97) for immunofluorescence assay (IFA).The ARCHITECT Chagas(®) assay demonstrates a sensitivity and specificity similar to ELISA and IFA assays; it allows a large volume of samples to be processed with a good standardization and reproducibility, as well as an objective interpretation.
Databáze: OpenAIRE