| Autor: |
P O, Attman, C, Knight-Gibson, M, Tavella, O, Samuelsson, P, Alaupovic |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Mineral and electrolyte metabolism. 18(2-5) |
| ISSN: |
0378-0392 |
| Popis: |
The dyslipoproteinemia of chronic renal failure (CRF) was characterized by discrete Apo B-containing lipoprotein particles separated by sequential immunoprecipitation of VLDL, IDL and LDL with antisera to Apo E and Apo C-III. CRF patients before and during dialysis had increased concentrations of Apo B-containing lipoproteins (LP) due to increased levels of triglyceride-rich LP-B:C and LP-B:C:E particles with no significant change in the levels of cholesterol-rich LP-B. Patients on hemodialysis had lower concentrations of LP-B:C and higher concentrations of LP-B:C:E than predialytic patients. The increase of Apo B-containing lipoprotein particles in CRF may contribute to atherosclerotic vascular disease and to glomerulosclerosis and progression of renal insufficiency. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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