Mesenchymal Stem Cells Differentiate to Endothelial Cells Using Recombinant Vascular Endothelial Growth Factor -A

Autor: Mohsen, Khaki, Ali Hatef, Salmanian, Hamid, Abtahi, Ali, Ganji, Ghasem, Mosayebi
Rok vydání: 2018
Předmět:
Zdroj: Reports of biochemistrymolecular biology. 6(2)
ISSN: 2322-3480
Popis: Vascular endothelial growth factor-A (VEGF-A), an endothelial cell-specific mitogen produced by various cell types, plays important roles in cell differentiation and proliferation. In this study we investigated the effect of recombinant VEGF-A on differentiation of mesenchymal stem cells (MSCs) to endothelial cells (ECs).VEGF-A was expressed inRecombinant VEGF-A was produced inRecombinant VEGF-A expressed in a prokaryotic system can induce MSCs differentiation to ECs and can be used in research and likely therapeutic applications.
Databáze: OpenAIRE